Ankle-Brachial Index in Patients With Nonvalvular Atrial Fibrillation

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Interrupting anticoagulation in patients with nonvalvular atrial fibrillation.

Three target-specific oral anticoagulants (TSOACs)-dabigatran, rivaroxaban, and apixaban-have been approved by the FDA to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation; however, no agents are currently approved to reverse the anticoagulant effects of these TSOACs in cases of active bleeding. This review discusses the benefits and risks of these...

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Periprocedural anticoagulation management of patients with nonvalvular atrial fibrillation.

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Cardioembolism, responsible for approximately one-third of cerebral infarctions in Japan, causes serious cerebral infarction with poor prognosis. Nonvalvular atrial fibrillation (NVAF) is the most important cause of cardioembolism. Both the occurrence of NVAF and the frequency of its progression to cerebral infarction increase with age. Timely introduction of warfarin depending on the presence ...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2014

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2013.09.071